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Semi-conservative DNA replication

DNA replication begins when the double helix unwinds and separates. Each old strand directs the formation of a new strand, so every resulting double helix has one old strand and one new strand.

In the picture

  1. Closed double helix: two blue strands wound together.
  2. Fork bead: enzyme at the point where the helix separates.
  3. One separated double helix: a blue strand paired with an orange strand.
  4. The other separated double helix: a blue strand paired with an orange strand.

Examples

  • A photocopy that keeps one original page and adds one fresh page.
  • A zipper opening: each side guides a matching new side.

Quiz: Semi-conservative DNA replication (Age 16)

  1. After DNA replication, what is true about each new DNA molecule?

    • It has one original strand and one newly made strand.
    • It has two newly made strands.
    • It has two original strands.
  2. How does an old DNA strand help build a new strand?

    • It is first copied into RNA, which then builds the new DNA.
    • Its bases pair with matching new bases according to the base-pairing rules.
    • It joins with any nearby strand without needing matching bases.
  3. What happens to the double helix at the start of DNA replication?

    • It breaks apart into individual bases.
    • It unwinds and separates into two strands.
    • It stays closed while new strands form outside it.

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Biology, Age 16