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A Gene and a Mutation

A gene is a set of instructions for building a protein. A mutation changes those instructions, so the protein may be missing or faulty, and a genetic disease can appear.

In the picture

  1. A colored segment on the twisted ladder strip: one gene’s place in the DNA.
  2. A dark bent rung on the copied strip: a mutation in the instruction.
  3. A two-part building machine: where the copied instruction is read to assemble a protein.
  4. A short bead chain: a protein that is missing a piece or folded wrong.
  5. Sagging muscle fibers: the visible effect of a faulty protein in a genetic disease.

Examples

  • Sickle cell disease: a change in hemoglobin makes red blood cells stiff and curved.
  • Cystic fibrosis: faulty salt channels make mucus thick in the lungs.

Quiz: A Gene and a Mutation (Age 13)

  1. What is a gene?

    • A set of instructions for building a protein
    • A protein that builds new genes
    • A disease caused by a mutation
  2. What does a mutation change?

    • The number of cells in the body
    • The position of the gene on the DNA
    • The instructions in a gene
  3. If a mutation makes a protein missing or faulty, what can appear?

    • A genetic disease
    • A stronger muscle
    • A new species

The answers, each with its explanation, are in the app. This lesson has left the free week, so its quiz is part of the subscription.

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Biology, Age 13